In vivo assessment of anticoagulant and antiplatelet ,

Background Syzygium cumini (L) Skeels is one of the very popular traditionally used medicinal plants with numerous pharmacological activities including antioxidant, hypoglycemic and anti-inflammatory However, actions of S cumini on blood coagulation and other parameters of blood were poorly pharmacologically studied Therefore, aim of this present investigation is to examine the effects ....

An Overview of Medicinal Plants as Potential Anti-Platelet ,

An Overview of Medicinal Plants as Potential Anti-Platelet Agents Mridul Bhowal1, Darshika M Mehta2 1B Pharm, PES College of Pharmacy, 50 feet road, Hanumanthanagar, , Chang FR, Wei JL, Teng CM, and Wu YC, Antiplatelet aggregation constituents from Annona purpurea, J Nat Prod, 61(12), 1998, 1457-61...

Antiplatelet aggregation activity of diterpene alkaloids ,

Aug 02, 2002· japonica var incisa, was found to selectively inhibit rabbit platelet aggregation induced by arachidonic acid in vitro and ex vivo and that the inhibition was much stronger than that of aspirin (Shen et al, 2000) In the present study, the antiplatelet aggregation activities of some natural atisine-type alkaloids isolated from S...

COMPARATIVE FUNCTION-STRUCTURAL ANALYSIS OF ,

flavonoids and their antiplatelet and antiradical activities are necessary to consider their modification into more potent and selective small-molecule inhibitors In current work we investigated the antiplatelet against ADP-induced platelet aggregation and antiradical (HOradical scavenging) activities of 8 flavonoid phytochemicals...

Comparative study of Antiplatelet Aggregation Activity of ,

Plant extracts having an antiplatelet aggregation activity may be a potential choice for development of anti-inflammatory drugs because of their natural origin The extraction of bioactive compounds being the most crucial step in the commercial development of natural products it is essential to have rapid and efficient phytochemical...

Molecules | Free Full-Text | Antiplatelet Aggregation ,

Bothcompounds 1 and 2 are active in the antiplatelet aggregation assay Interestingly, thepossible acetonide artifact 1 displayed significant antiplatelet aggregation induced not onlyby AA and collagen but also by platelet activating factor (PAF) View Full-Text...

antiplatelet aggregation plants - greenrevolutionorgin

Antiplatelet Aggregation Coumarins from the Leaves of Murraya omphalocarpa204 Кб Both compounds 1 and 2 are active in the antiplatelet aggregation assayPlant Material Fresh leaves of M omphalocarpa were collected from Pingtung County, Taiwan, in September 1999, and....

Coumarins and antiplatelet aggregation constituents from ,

The structure of new compound 3 thus was elucidated as ( +__ )-cis-4'-tigloylkhellactone Compound 4, [~t]2D6: + 254(CHC13, c014), was iso- lated as prisms and the molecular formula was estab- lished as C19H2006 by E1 and HR mass spectrometry Coumarins and Antiplatelet Aggregation constituents from Formosan Peucedanum japonicum 527 Table 1...

Frontiers | A Novel Antiplatelet Aggregation Target of ,

And the platelet aggregation-related genes were discovered in databases, and antiplatelet aggregation-related gene targets were selected through comparison The functions of target genes and related pathways were analyzed and screened using the DAVID database, and the network was constructed using Cytoscape software...

Antiplatelet, anticoagulant, and profibrinolytic ,

May 22, 2014· Abstract Baicalin is a flavonoid compound purified from the medicinal plant Scutellaria baicalensis Georgi and has been reported to possess anti-inflammatory and anti-viral activiti However, antiplatelet, anticoagulant, and profibrinolytic properties of baicalin have not been studied...

Flavonoid and Screening and Antiplatelet Aggregration ,

The inhibitory concentration (IC 50 ) yielded a concentration of 675 mg/mL and proved an inhibitory effect on platelet aggregation A non-violet gel formation indicated inhibition and manifested both for fruit extract and aspirin Hence, it is potent antiplatelet aggregation activity...

Plant Alkaloids as Antiplatelet Agent: Drugs of the Future ,

Sep 22, 2016· Antiplatelet mechanism of plant alkaloids Various mechanisms have been proposed for the antiplatelet activity of different isolated plant-alkaloids (Figure (Figure1) 1)Researchers have proposed that berberine significantly inhibited platelet aggregation by inhibiting synthesis of thromboxane A2 induced by adenine diphosphate, arachidonic acid, collagen (Chu et al, 1996)...

Anti-platelet aggregation assay and chemical composition ,

Anti-platelet aggregation assay and chemical composition of essential oil from Allium atroviolaceum Boiss growing in Iran Zahra Lorigooini 1,4, Farzad Kobarfard 2,3*, Seyed Abdolmajid Ayatollahi 1,3 1Department of Pharmacognosy, School of Pharmacy, Shahid Beheshti University of ,...

In vitro antiplatelet activity-guided fractionation of ,

Apr 26, 2005· To determine the in vitro antiplatelet aggregation property, 100 μl of the various fractions of the plant, in different concentrations (100 μg/ ml, 200 μg/ml, 400 μg/ml, 500 μg/ml), respectively was added to the platelet suspension at different concentrations for 1 min exposure at 37° before treatment with platelet aggregating agents ....

Positive Health Online | Article - Coleus forskohlii ,

The problem with whole plant extracts of Coleus is that so far, most of the research has been carried out on the isolated constituent forskolin, although some sources suggest that clinical results using the whole plant are better The forskolin content of the root is generally 02-03% and it may not be enough to produce the desired effect...

Medicinal Plants with Antiplatelet Activity

The identification and/or structure modification of the plant constituents and the understanding of their action mechanisms will be helpful in the development of new antiplatelet agents based on medicinal plants which could contribute to the prevention of thromboembolic-related disorders by inhibiting platelet aggregation...

In Vitro Platelet Aggregation Inhibition Activity of ,

the percent antiplatelet activity with the succeeding formula: % Inhibition of Platelet Aggregation = The percent inhibition of platelet aggregation values compares the absorbance readings among treated (with plant extract or aspirin) controls and the untreated control Percent Antiplatelet Activity...

Evaluation of selected South African plant species for ,

Evaluation of selected South African plant species for antioxidant, antiplatelet, and cytotoxic activity M M Suleiman1,2, V Bagla1, , was used to determine the inhibitory effect of the plant extracts on platelet aggregation Briefly, fresh equine (Equus caballus) ....

Antiplatelet, anticoagulant, and profibrinolytic ,

May 22, 2014· Abstract Baicalin is a flavonoid compound purified from the medicinal plant Scutellaria baicalensis Georgi and has been reported to possess anti-inflammatory and anti-viral activiti However, antiplatelet, anticoagulant, and profibrinolytic properties of baicalin have not been studied...

Antiplatelet aggregating activity of extracts of ,

Request PDF on ResearchGate | Antiplatelet aggregating activity of extracts of Indonesian medicinal plants I | Eight Indonesian medicinal plants (Cassia alata ,...

Antiplatelet Aggregation Coumarins from the Leaves of ,

antiplatelet aggregation induced by arachidonic acid (AA) and collagen [4] In the continuing phytochemical investigation, two coumarins, minumicroline acetonide (1) [5-6] and epimurpaniculol senecioate (2), were isolated from the methanoic extracts of the leaves of this plant by the way of bioactivity-guided fractionation method...

Antiplatelet Aggregation Coumarins from the Leaves of ,

antiplatelet aggregation induced by arachidonic acid (AA) and collagen [4] In the continuing phytochemical investigation, two coumarins, minumicroline acetonide (1) [5-6] and epimurpaniculol senecioate (2), were isolated from the methanoic extracts of the leaves of this plant by the way of bioactivity-guided fractionation method...

Kamuning / Murraya paniculata / orange jessamine ,

Kamuning, Murraya paniculata, orange JASMINE: Philippine Herbal Medicine - An illustrated compilation of medicinal plants in the Philippines by Dr Godofredo Stuart, with botanical information, chemical properties and folkloric uses and medicinal studies...

The pyrrolidinoindoline alkaloid Psm2 inhibits platelet ,

Jul 18, 2016· Psm2, one of the pyrrolidinoindoline alkaloids isolated from whole Selaginella moellendorffii plants, has shown a potent antiplatelet activity In this study, we further evaluated the antiplatelet ....

A New Antiplatelet Diarylheptanoid from Alpinia ,

A new diarylheptanoid, 1,7-bis(4-hydroxyphenyl)-3-hydroxy-1,3-heptadien-5-one (1), along with seven other known compounds, were isolated from the seeds of Alpinia blepharocalyx Of these, compounds 1 and 3 showed strong inhibition of collagen-induced, arachidonic acid-induced, and adenosine diphosphate-induced platelet aggregation of human whole blood...

ANTIPLATELET AYURVEDIC HERBS IN THE MANAGEMENT ,

ANTIPLATELET AYURVEDIC HERBS IN THE MANAGEMENT OF CARDI-OVASCULAR DISEASE-A REVIEW Vidhya Unnikrishnan1, Nishteswar K 2 1 PhD scholar, 2 Professor& Head, Department of Dravyaguna, IPGT&RA, GAU, Jamnagar, Gujarat, India INTRODUCTION Cardiovascular disease (C VD), in-cluding heart disease and stroke, is the...

Inhibitory Effect of Lantana camara L, Eclipta prostrata ,

If the rupture is very large, then most likely there will be a blockage in the large blood vessels 1 The formation of such thrombus is medically preventable with antiplatelet aggregation agents Some of medicinal plants from Indonesia have hemostasis-related activities eg Lantana camara L, Eclipta prostrata (L) L) dan Cosmos caudatus Kunth)...

The pyrrolidinoindoline alkaloid Psm2 inhibits platelet ,

Jul 18, 2016· Psm2, one of the pyrrolidinoindoline alkaloids isolated from whole Selaginella moellendorffii plants, has shown a potent antiplatelet activity In this study, we further evaluated the antiplatelet ....

ANTIPLATELET AYURVEDIC HERBS IN THE MANAGEMENT ,

ANTIPLATELET AYURVEDIC HERBS IN THE MANAGEMENT OF CARDI-OVASCULAR DISEASE-A REVIEW Vidhya Unnikrishnan1, Nishteswar K 2 1 PhD scholar, 2 Professor& Head, Department of Dravyaguna, IPGT&RA, GAU, Jamnagar, Gujarat, India INTRODUCTION Cardiovascular disease (C VD), in-cluding heart disease and stroke, is the...

Kamuning / Murraya paniculata / orange jessamine ,

Kamuning, Murraya paniculata, orange JASMINE: Philippine Herbal Medicine - An illustrated compilation of medicinal plants in the Philippines by Dr Godofredo Stuart, with botanical information, chemical properties and folkloric uses and medicinal studies...